Understanding how bacteria contribute to gum disease
Biofilm Spatial Structure in the Transition from Health to Periodontal Disease
This study is looking at how certain bacteria in your mouth can cause gum disease by seeing how they interact with your immune system, and it’s for anyone interested in understanding more about what leads to gum problems in both people and dogs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Albany NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10892307 on NIH RePORTER |
What this research studies
This research investigates the role of specific bacteria in the development of periodontal disease, focusing on how these bacteria interact with the immune system and contribute to inflammation. By examining biofilms on teeth from both humans and dogs, the study aims to identify structural features that are common in disease progression. Researchers will use advanced imaging techniques to visualize these biofilms and analyze the genetic expression of bacteria involved in gum disease. This comprehensive approach seeks to uncover the mechanisms that lead to gum inflammation and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals over 21 years old who are experiencing symptoms of periodontal disease.
Not a fit: Patients with no signs of periodontal disease or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating periodontal disease.
How similar studies have performed: Previous research has shown success in understanding the role of bacterial communities in periodontal disease, making this approach both relevant and promising.
Where this research is happening
Albany, United States
- State University of New York at Albany — Albany, United States (Active)
Researchers
- Principal investigator: Valm, Alex M — State University of New York at Albany
- Study coordinator: Valm, Alex M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.