Understanding how bacteria communicate to control Salmonella infections
Interspecies Bacterial Signaling to Regulate Salmonella Virulence
This study is looking at how certain chemicals in our intestines can help stop Salmonella bacteria, which cause food poisoning, from making us sick, and it aims to find new ways to keep us healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project ID | NIH-11073093 on NIH RePORTER |
What this research studies
This research investigates how chemical signals in the intestines can influence the behavior of Salmonella bacteria, which are responsible for foodborne illnesses. By studying the interactions between these bacteria and the host's microbiota, the researchers aim to uncover how certain molecules can inhibit Salmonella's ability to invade the intestinal lining. The approach involves analyzing these chemical signals and their effects on bacterial virulence, with the goal of finding new ways to prevent infections in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are at risk of Salmonella infections, particularly those with compromised immune systems or underlying health conditions.
Not a fit: Patients who are not at risk for Salmonella infections or those who have already developed severe illness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing Salmonella infections, reducing the incidence of foodborne illnesses.
How similar studies have performed: Previous research has shown promise in using interspecies signaling to modulate bacterial behavior, suggesting that this approach could be effective.
Where this research is happening
Ithaca, United States
- Cornell University — Ithaca, United States (Active)
Researchers
- Principal investigator: Altier, Craig — Cornell University
- Study coordinator: Altier, Craig
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.