Understanding how bacteria communicate and cooperate
Bacterial quorum sensing
['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-11087399
This study looks at how certain bacteria, like Pseudomonas aeruginosa, talk to each other and work together, which could help us find new ways to fight infections and improve treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11087399 on ClinicalTrials.gov |
What this research studies
This research investigates how bacteria, particularly Pseudomonas aeruginosa, communicate with each other through a process called quorum sensing. By studying the chemical signals that bacteria use to coordinate their activities, the research aims to uncover the biological principles behind their social interactions. The approach involves examining the molecular mechanisms of these signals and how they influence bacterial behavior, which could lead to new strategies for disrupting harmful bacterial communities. Patients may benefit from insights gained in developing new antibacterial therapies targeting these communication pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from bacterial infections, particularly those caused by antibiotic-resistant strains.
Not a fit: Patients with viral infections or non-bacterial conditions are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that effectively combat bacterial infections by disrupting their communication systems.
How similar studies have performed: Previous research has shown promise in targeting bacterial communication systems, indicating that this approach could lead to significant advancements in antibacterial therapies.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GREENBERG, EVERETT P — UNIVERSITY OF WASHINGTON
- Study coordinator: GREENBERG, EVERETT P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.