Understanding how bacteria become resistant to antibiotics
Bioinformatics Core
This study is looking at how some bacteria become resistant to antibiotics, which can make infections harder to treat, and it aims to find better ways to understand and tackle these tough infections to help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10911821 on NIH RePORTER |
What this research studies
This research focuses on the mechanisms that lead to antibiotic resistance in bacteria, particularly how certain cell states contribute to treatment failures. By developing and sharing advanced genomic and bioinformatics methods, the project aims to analyze bacterial genomes and identify the factors that enable resistance. Patients may benefit from improved understanding and treatment strategies for infections caused by resistant bacteria. The research involves collaboration and training to ensure effective use of these methods across various scientific projects.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients suffering from bacterial infections that are difficult to treat due to antibiotic resistance.
Not a fit: Patients with viral infections or those not affected by antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for bacterial infections, particularly those that are currently resistant to antibiotics.
How similar studies have performed: Other research has shown success in using bioinformatics and genomic approaches to tackle antibiotic resistance, indicating that this approach is both relevant and promising.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Cooper, Vaughn — Boston Children's Hospital
- Study coordinator: Cooper, Vaughn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.