Understanding how B cells contribute to multiple sclerosis
The Role of B cells in the Origin and Progression of Multiple Sclerosis
This study is looking at how certain immune cells called B cells might affect the start and progression of multiple sclerosis (MS), with the goal of finding better ways to treat the condition for people living with it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11078205 on NIH RePORTER |
What this research studies
This research investigates the role of B cells in the onset and progression of multiple sclerosis (MS), a chronic autoimmune disease affecting the central nervous system. By examining patient cohorts and utilizing advanced technologies like high-field MRI and genetic analysis, the study aims to identify the triggers of MS and factors that influence its progression. The focus is on characterizing the molecular diversity of B cells and their receptors at different stages of the disease, which could lead to improved therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with multiple sclerosis, particularly those in the early stages of the disease.
Not a fit: Patients with other neurological conditions or those who are not diagnosed with multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients with multiple sclerosis.
How similar studies have performed: Previous research has shown promising results in understanding the role of B cells in autoimmune diseases, indicating potential for success in this area.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Hauser, Stephen L — University of California, San Francisco
- Study coordinator: Hauser, Stephen L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.