Understanding how B-cell lymphomas develop through epigenetic changes
Targeting Epigenetic Circuits in B-Cell Lymphomas
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10926827
This study is looking into how changes in the way B-cells are controlled can lead to B-cell lymphomas, with the goal of finding new ways to help treat patients with this type of cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10926827 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind the development of B-cell lymphomas, focusing on how disruptions in epigenetic regulation affect B-cell behavior. The principal investigator aims to uncover the processes that lead to malignant transformation in B-cells, particularly during their activation in the germinal center. By studying these changes, the research seeks to identify potential therapeutic targets that could improve treatment outcomes for patients with B-cell lymphomas.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with B-cell lymphomas, such as follicular lymphoma or diffuse large B-cell lymphoma.
Not a fit: Patients with other types of cancers or non-cancerous conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies that specifically target the underlying mechanisms of B-cell lymphomas.
How similar studies have performed: Previous research in cancer epigenetics has shown promising results, indicating that targeting epigenetic mechanisms can be an effective approach in treating various cancers.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MELNICK, ARI M. — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: MELNICK, ARI M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brill-Symmers Disease