Understanding how B and T cells can protect against and eliminate SIV/SHIV infections

B and T Cell Biology of Protection from and Eradication of SIV/SHIV Infection

NIH-funded research Emory University · NIH-11109653

This study is looking at how certain immune cells can help fight off HIV and improve vaccines, so people living with the virus might have better options for treatment and protection in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11109653 on NIH RePORTER

What this research studies

This research investigates the immune mechanisms that enable B and T cells to protect against and potentially eradicate SIV/SHIV infections. By utilizing advanced techniques, the study aims to characterize the immune responses generated by a novel vaccine designed to elicit strong and sustained immunity. The research focuses on how these immune cells interact with the virus and the body's tissues, particularly in the context of reducing viral reservoirs after stopping antiretroviral therapy. Patients may benefit from insights that could lead to improved vaccines and therapies for HIV/AIDS.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research are individuals at risk for HIV or those living with HIV who are seeking innovative treatment options.

Not a fit: Patients who are not at risk for HIV or those who are not infected with the virus may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective vaccines and treatments for HIV/AIDS, improving patient outcomes.

How similar studies have performed: Previous research has shown promise in similar approaches, particularly in the development of vaccines that elicit strong immune responses against HIV.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.