Understanding how avian influenza viruses evolve and affect immune responses

NIAID CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND RESPONSE: AVIAN INFLUENZA RESEARCH

NIH-funded research St. Jude Children's Research Hospital · NIH-11261572

This study is looking at how the H5N1 bird flu virus spreads and affects both people and animals, with the hope of finding better ways to protect against it through improved vaccines and understanding of our immune responses.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Jude Children's Research Hospital NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-11261572 on NIH RePORTER

What this research studies

This research investigates the factors that influence the evolution and transmission of avian influenza viruses, particularly the H5N1 strain. It involves studying both human and animal samples to gain insights into how these viruses spread and how the immune system responds to them. By conducting cohort studies, the research aims to identify immunological factors that can help improve vaccination strategies and disease outcomes. The ultimate goal is to enhance our understanding of how to protect against influenza infections.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals who have been exposed to avian influenza or are at risk of infection, as well as those involved in poultry farming.

Not a fit: Patients who are not at risk of avian influenza or those with no history of exposure to influenza viruses may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccines and treatments for influenza, potentially reducing the impact of future outbreaks.

How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for meaningful advancements.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Disease Outcome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.