Understanding how avian influenza viruses evolve and affect immune responses
NIAID Centers of Excellence for Influenza Research and Response: Avian Influenza Research Activities
This study looks at how bird flu viruses change and spread, and how both people and animals react to them, to help us better understand how vaccines can protect us and improve ways to prevent outbreaks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11259409 on NIH RePORTER |
What this research studies
This research investigates the factors that influence the evolution and transmission of avian influenza viruses, focusing on both human and animal responses to infection. It involves cohort studies and sampling to gather data on how these viruses adapt and how the immune system responds to them. By identifying the immunological factors that affect disease outcomes, the research aims to enhance our understanding of vaccination and protection against influenza. The findings could lead to improved strategies for managing and preventing influenza outbreaks.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals who are at risk of avian influenza exposure, such as those working in agriculture or healthcare settings.
Not a fit: Patients who are not at risk of avian influenza or those with no history of influenza-related complications may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better vaccines and treatments for influenza, ultimately reducing the impact of the virus on public health.
How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has the potential for meaningful advancements.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Hensley, Scott — University of Pennsylvania
- Study coordinator: Hensley, Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.