Understanding how avian influenza viruses evolve and affect humans
NIAID Centers of Excellence for Influenza Research and Response: Avian Influenza Research Activities
This study is looking at how the H5N1 bird flu virus spreads and how both people and animals react to it, with the hope of finding better ways to protect against it through vaccines and treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11259410 on NIH RePORTER |
What this research studies
This research investigates the factors that influence the evolution and transmission of avian influenza viruses, particularly the H5N1 strain. It involves studying both human and animal responses to these viruses through cohort studies and sampling. The goal is to enhance our understanding of how these viruses spread and how the immune system responds to them, which could lead to better vaccination strategies and treatments. By examining environmental and molecular factors, the research aims to identify ways to improve protection against influenza.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with a history of avian influenza exposure or those at high risk for influenza infections.
Not a fit: Patients who are not at risk for influenza infections or those without a history of exposure to avian influenza may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for influenza, potentially reducing the impact of avian flu on human health.
How similar studies have performed: Previous research has shown success in understanding influenza virus behavior and immune responses, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Hensley, Scott — University of Pennsylvania
- Study coordinator: Hensley, Scott
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.