Understanding how autophagy affects kidney disease in diabetes
Autophagy in Diabetic Kidney Disease
['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-11031987
This study is looking at how a process that helps keep kidneys healthy might affect people with diabetes who have kidney problems, with the hope of finding better ways to diagnose and treat their condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11031987 on ClinicalTrials.gov |
What this research studies
This research investigates the role of autophagy, a cellular process that helps maintain kidney health, in diabetic kidney disease (DKD). By examining kidney samples and clinical data from patients with diabetes, the study aims to uncover the molecular mechanisms that contribute to the variability in DKD symptoms and progression. The goal is to develop personalized diagnostic and treatment strategies based on these findings, which could lead to better management of kidney health in diabetic patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with diabetes who are experiencing or at risk for diabetic kidney disease.
Not a fit: Patients without diabetes or those with kidney disease unrelated to diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with diabetic kidney disease.
How similar studies have performed: Previous research has shown promising results in understanding autophagy in experimental models of diabetes, but this approach in human diabetic kidney disease is relatively novel.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIMONTE, CHRISTINE — UNIVERSITY OF WASHINGTON
- Study coordinator: LIMONTE, CHRISTINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus