Understanding how autophagy affects gut health and inflammation
HIF-Regulated Autophagy in Host-microbe Interactions
['FUNDING_OTHER'] · VA EASTERN COLORADO HEALTH CARE SYSTEM · NIH-10951497
This study is looking at how a natural recycling process in our cells might affect inflammatory bowel disease (IBD) in military veterans, with the hope of finding new treatments to help people dealing with this condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA EASTERN COLORADO HEALTH CARE SYSTEM (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10951497 on ClinicalTrials.gov |
What this research studies
This research investigates the role of autophagy, a cellular recycling process, in the context of inflammatory bowel disease (IBD), particularly among military veterans. By studying animal models, the research aims to uncover the molecular mechanisms that contribute to IBD and how these processes interact with gut bacteria. The goal is to identify potential new therapies that can improve treatment outcomes for patients suffering from chronic gastrointestinal inflammation.
Who could benefit from this research
Good fit: Ideal candidates for this research are military veterans experiencing symptoms of inflammatory bowel disease.
Not a fit: Patients who do not have inflammatory bowel disease or are not military veterans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for inflammatory bowel disease with fewer side effects.
How similar studies have performed: Previous research has shown promising results in understanding autophagy's role in gut health, suggesting that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- VA EASTERN COLORADO HEALTH CARE SYSTEM — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DOWDELL, ALEXANDER SHEA — VA EASTERN COLORADO HEALTH CARE SYSTEM
- Study coordinator: DOWDELL, ALEXANDER SHEA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.