Understanding how autistic adolescents process rewards
Neural mechanism of reward processing in autistic adolescents
['FUNDING_R21'] · TEMPLE UNIV OF THE COMMONWEALTH · NIH-10948847
This study looks at how teenagers with autism respond to rewards in social situations compared to their peers without autism, using brain scans to understand the differences, and it's aimed at helping improve social interactions for young people aged 10-15.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEMPLE UNIV OF THE COMMONWEALTH (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10948847 on ClinicalTrials.gov |
What this research studies
This research investigates how adolescents with autism spectrum disorder (ASD) respond to rewards, particularly in social situations. By comparing brain activity in autistic youths to neurotypical peers using functional MRI, the study aims to uncover differences in reward processing. The focus is on adolescents aged 10-15, a critical developmental period for social interactions. The research seeks to identify the neural mechanisms behind reduced responses to social rewards, which could inform future interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 10-15 diagnosed with autism spectrum disorder.
Not a fit: Patients outside the age range of 10-15 or those without a diagnosis of autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapeutic strategies that enhance social motivation and engagement in autistic adolescents.
How similar studies have performed: Previous research has shown promise in understanding reward processing in autism, but this study aims to address specific gaps, making it a novel approach.
Where this research is happening
PHILADELPHIA, UNITED STATES
- TEMPLE UNIV OF THE COMMONWEALTH — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JARCHO, JOHANNA MOLLY — TEMPLE UNIV OF THE COMMONWEALTH
- Study coordinator: JARCHO, JOHANNA MOLLY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder