Understanding how ATG2 protein helps transport lipids in cells
Official title: ATG2 mediated lipid transport is essential for lipid droplet homeostasis
Funded at Yale University · NIH-10806981 · Data updated 2026-11-12
This study is looking at how a protein called ATG2 helps move fats around in our cells, which is important for keeping our energy balanced and our cells healthy, and it could help people with conditions like obesity and fatty liver disease understand more about their health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31DK136246-02 |
| Project ID | NIH-10806981 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals suffering from metabolic disorders such as obesity, diabetes, or fatty liver disease.
✕Less likely to help
Patients without metabolic disorders or those not experiencing issues related to lipid metabolism may not benefit from this research.
What this research studies
This research investigates the role of the ATG2 protein in the transport of lipids within cells, which is crucial for maintaining energy balance and cellular health. By examining how ATG2 facilitates the movement of lipids from lipid droplets to other organelles, the study aims to uncover mechanisms that could be disrupted in metabolic disorders like obesity and fatty liver disease. The approach includes laboratory experiments to observe lipid transport processes and the effects of ATG2 deletion on cellular function. Patients with metabolic disorders may find insights from this research applicable to their conditions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating metabolic disorders by targeting lipid transport mechanisms.
How similar studies have gone: Other research has shown promising results in understanding lipid transport mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Korfhage, Justin — Yale University
- Study coordinator: Korfhage, Justin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.