Understanding how Ascaris infections cause allergic airway disease in children.
Discovering the Immunologic Mechanism of Ascaris-induced Allergic Airway Disease.
This study is looking at how infections from a common worm called Ascaris affect children's immune systems, especially those living in poverty, to find better ways to prevent and treat related health problems like asthma.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10763018 on NIH RePORTER |
What this research studies
This research investigates the immune responses triggered by Ascaris infections, which are common in children living in poverty and can lead to allergic airway diseases like asthma. The project aims to uncover the mechanisms by which these parasitic infections affect children's health, focusing on the immune system's reaction. By combining laboratory research with field studies, the goal is to identify new ways to prevent and treat the health issues caused by these infections. The research is led by Dr. Jill Weatherhead, who collaborates with experts in immunology and parasitology to ensure a comprehensive approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are living in poverty and are at risk for Ascaris infections.
Not a fit: Patients who do not have Ascaris infections or are not experiencing allergic airway diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and preventive measures for allergic airway diseases in children affected by Ascaris infections.
How similar studies have performed: Previous research has shown promising results in understanding the immune responses to parasitic infections, indicating that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Weatherhead, Jill Elizabeth — Baylor College of Medicine
- Study coordinator: Weatherhead, Jill Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.