Understanding how arsenic is transported and transformed in the body
MECHANISMS OF ARSENIC TRANSPORT AND BIOTRANSFORMATIONS
This study is looking at how arsenic, a harmful substance found in the environment, moves and changes in our bodies, with the goal of understanding how it can affect our health, especially in relation to cancer and other diseases, so that we can find better ways to help those exposed to arsenic.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida International University NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project ID | NIH-10806244 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which arsenic, a harmful environmental toxin, is transported and transformed within biological systems. The team aims to identify specific enzymes involved in arsenic biotransformation and their roles in modifying arsenic's toxicity and mobility. By utilizing biochemical and structural analysis, the research will also explore how these processes can affect human health, particularly in relation to cancer and other diseases linked to arsenic exposure. Patients may benefit from insights gained into arsenic's effects and potential treatments for arsenic-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals exposed to arsenic through environmental sources or those with arsenic-related health conditions, such as bladder cancer.
Not a fit: Patients who have not been exposed to arsenic or do not have related health conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of arsenic exposure, potentially reducing cancer risk and other health issues associated with arsenic.
How similar studies have performed: Previous research has shown success in understanding arsenic transport and biotransformation, indicating that this approach is building on established findings in the field.
Where this research is happening
Miami, United States
- Florida International University — Miami, United States (Active)
Researchers
- Principal investigator: Rosen, Barry P. — Florida International University
- Study coordinator: Rosen, Barry P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.