Understanding how arsenic exposure affects health across generations
Official title: A mechanistic approach to understand the tissue-specific development of toxicity in response totransgenerational chronic arsenic exposures
Funded at Keene State College · NIH-11043837 · Data updated 2026-11-12
This study is looking at how long-term exposure to arsenic can cause health problems not just for the person exposed, but also for their children and grandchildren, and it aims to understand how this happens in the body.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Keene State College NIH-funded |
| Lab location | 1 site (Keene, United States) |
| Project start | December 24, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $379,504 |
| NIH project number | 1R15ES037123-01 |
| Project ID | NIH-11043837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a history of arsenic exposure, particularly those from areas with known environmental contamination.
✕Less likely to help
Patients who have not been exposed to arsenic or who do not have a family history of related health issues may not benefit from this research.
What this research studies
This research investigates how chronic exposure to arsenic can lead to health issues that affect not just the individual exposed, but also their descendants. By studying a model organism, researchers aim to uncover the mechanisms behind tissue-specific toxicity and how arsenic accumulates in certain body tissues over generations. The study will analyze genetic and molecular changes that occur due to arsenic exposure, providing insights into the long-term effects of environmental toxins on health. This research could help identify vulnerable populations and inform public health strategies.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of health issues related to arsenic exposure in affected communities.
How similar studies have gone: While there has been research on arsenic toxicity, this specific approach examining transgenerational effects and tissue-specific responses is relatively novel.
Where this research is happening
-
Keene State College
Keene, United States Active
Researchers
- Principal investigator: Roy Chowdhury, Priyanka — Keene State College
- Study coordinator: Roy Chowdhury, Priyanka
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.