Understanding how arenaviruses are built
Study of arenavirus assembly
['FUNDING_R01'] · GEORGIA STATE UNIVERSITY · NIH-11123168
This project looks at how a specific virus, called LCMV, is put together and how it works, to help us fight infections.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGIA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11123168 on ClinicalTrials.gov |
What this research studies
This project focuses on understanding the detailed structure and assembly process of the lymphocytic choriomeningitis virus (LCMV), which is a human pathogen carried by rodents. We aim to discover how the virus's various components, such as its genetic material and proteins, come together to form a complete, infectious virus. Currently, we don't fully understand the virus's internal organization or how it assembles itself. By mapping these structures, we hope to identify new weaknesses that could be targeted to stop the virus from forming and spreading, drawing lessons from recent pandemics caused by similar zoonotic pathogens.
Who could benefit from this research
Good fit: This foundational research does not involve patient participation, but aims to benefit anyone susceptible to arenavirus infections in the future.
Not a fit: Patients currently suffering from arenavirus infections would not directly benefit from this basic research, as it is not a clinical trial.
Why it matters
Potential benefit: If successful, this work could lead to the development of new antiviral drugs or treatments that specifically target the assembly process of arenaviruses, preventing them from causing illness.
How similar studies have performed: While individual parts of these viruses have been studied, this project explores the overall structure and assembly, which is a new area of focus.
Where this research is happening
ATLANTA, UNITED STATES
- GEORGIA STATE UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUO, MING — GEORGIA STATE UNIVERSITY
- Study coordinator: LUO, MING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.