Understanding how anxiety treatment affects brain function in older adults with dementia
Official title: Mechanism, connectivity, and outcome prediction of anxiety intervention from MRI-derived models in tDCS augmented cognitive training
Funded at University of Florida · NIH-10997645 · Data updated 2026-11-12
This study is looking at how certain treatments, like brain stimulation and mental exercises, can help older adults with Alzheimer's and related conditions who are feeling anxious, with the goal of finding better ways to support their mental health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | August 16, 2024 |
| Project end | August 15, 2026 |
| Funding year | 2024 |
| Award (this year) | $43,902 |
| NIH project number | 1F31AG087647-01A1 |
| Project ID | NIH-10997645 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults diagnosed with mild cognitive impairment or Alzheimer's disease who also experience anxiety.
✕Less likely to help
Patients without a diagnosis of mild cognitive impairment or Alzheimer's disease, or those who do not experience anxiety, may not benefit from this research.
What this research studies
This research investigates the effects of anxiety interventions on older adults with Alzheimer's disease and related dementias. It utilizes transcranial direct current stimulation (tDCS) combined with cognitive training to explore how these treatments influence brain connectivity and individual responses. By employing functional magnetic resonance imaging (fMRI), the study aims to identify specific brain regions involved in the treatment response, which could lead to more personalized care for patients experiencing anxiety alongside cognitive decline.
Why it matters
Potential benefit: If successful, this research could lead to improved anxiety treatments that enhance the quality of life for patients with Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in using tDCS for treating anxiety, but this specific approach focusing on Alzheimer's disease and related dementias is relatively novel.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Stolte, Skylar E — University of Florida
- Study coordinator: Stolte, Skylar E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.