Understanding how antiretroviral drugs affect breastfeeding women and their infants
PHARMACOKINETIC AND SAFETY OF ANTIRETROVIRAL AND RELATED DRUGS IN LACTATING WOMEN AND BREASTFED INFANTS STUDY
This study is looking at how certain medications for HIV are handled in breastfeeding mothers and how these drugs might get into their breastmilk, which could affect their babies, so we're collecting samples from both moms and their infants to learn more about this important topic.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10910823 on NIH RePORTER |
What this research studies
This research investigates how antiretroviral and related drugs are processed in lactating women and how these drugs transfer into breastmilk, potentially affecting breastfed infants. By collecting blood and breastmilk samples from mothers and blood samples from infants, the study aims to gather important pharmacokinetic data. The approach is designed to minimize risks to participants while maximizing the efficiency of data collection, focusing on drugs that are often overlooked in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are lactating women who are receiving antiretroviral therapy and their breastfed infants.
Not a fit: Patients who are not lactating or who are not receiving antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer medication guidelines for lactating women, ensuring better health outcomes for both mothers and their infants.
How similar studies have performed: Previous research has shown success in studying pharmacokinetics in similar populations, but this specific focus on lactating women and infants is relatively novel.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Benjamin, Daniel — Duke University
- Study coordinator: Benjamin, Daniel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.