Understanding how antibodies respond to respiratory infections and vaccinations
Official title: Core C - Proteomics Core
Funded at Washington University · NIH-10824577 · Data updated 2026-11-12
This study is looking at how your body makes antibodies after getting sick with viruses like the flu or COVID-19, or after getting vaccinated, to better understand how these antibodies work to protect you from infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 4, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $359,802 |
| NIH project number | 1U19AI181103-01 |
| Project ID | NIH-10824577 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals who have been vaccinated against or infected with influenza or SARS-CoV-2.
✕Less likely to help
Patients who have not been vaccinated or infected with these viruses may not benefit from this research.
What this research studies
This research focuses on analyzing the antibodies produced in response to infections like influenza and SARS-CoV-2, as well as after vaccinations. It will investigate the molecular makeup and dynamics of these antibodies in the blood and respiratory tract. By using advanced technologies, the research aims to sequence and functionally analyze the B cell receptors that are crucial for immune responses. This comprehensive approach will help in understanding how effective these antibodies are in fighting infections.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for respiratory infections.
How similar studies have gone: Previous research has shown success in analyzing antibody responses to infections, making this approach promising.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Georgiou, George Georgiou — Washington University
- Study coordinator: Georgiou, George Georgiou
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.