Understanding how antibodies recognize viruses that cause respiratory infections in children.
Official title: Antibody recognition of paramyxovirus surface proteins
Funded at Florida State University · NIH-11131477 · Data updated 2026-11-12
This study is looking at how to create special antibodies to help fight off parainfluenza viruses, which can make young children sick with respiratory infections, and it aims to find out how these antibodies can better protect kids and others with weakened immune systems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project start | August 16, 2024 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $682,008 |
| NIH project number | 1R56AI181850-01 |
| Project ID | NIH-11131477 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include young children under the age of five who are at risk for respiratory infections, as well as immunocompromised adults.
✕Less likely to help
Patients who are not at risk for respiratory infections or who are older adults without underlying health conditions may not benefit from this research.
What this research studies
This research focuses on developing monoclonal antibodies to combat parainfluenza viruses, which are a significant cause of respiratory infections in young children. The study aims to identify the structural features of the virus's surface proteins that are crucial for neutralizing the virus. By understanding how these antibodies work, the research hopes to improve prevention and treatment strategies for infections caused by these viruses. The findings could lead to better therapeutic options for both children and immunocompromised adults.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce respiratory infections caused by parainfluenza viruses in children.
How similar studies have gone: Previous research has shown success in developing monoclonal antibodies for other respiratory viruses, indicating a promising potential for this approach.
Where this research is happening
-
Florida State University
Tallahassee, United States Active
Researchers
- Principal investigator: Mousa, Jarrod — Florida State University
- Study coordinator: Mousa, Jarrod
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.