Understanding how antibodies can prevent and treat HIV infection
Impact of Antibody Effector Function Diversity on Antiviral Activity In Situ
This study is looking at how different types of antibodies help fight HIV, with the hope of finding ways to create better vaccines and treatments for people living with the virus.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10894640 on NIH RePORTER |
What this research studies
This research investigates the role of diverse antibody functions in combating HIV infection. By examining how antibodies interact with immune cells in the body, the study aims to uncover the mechanisms that enhance antiviral activity. The approach includes analyzing immune responses in both human and animal models to identify effective antibody characteristics. The ultimate goal is to inform the design of better vaccines and treatments for HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk of HIV infection or those living with HIV who are seeking new treatment options.
Not a fit: Patients who are not at risk for HIV or those who are already receiving effective treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective vaccines and therapies for preventing and treating HIV infection.
How similar studies have performed: Previous research has shown promise in understanding antibody functions in HIV, suggesting that this approach could lead to significant advancements.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Tomaras, Georgia Doris — Duke University
- Study coordinator: Tomaras, Georgia Doris
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.