Understanding how antibodies can help control virus infections
Official title: The role of cell, antigen, and antibody, in controlling virus infection through Fc-dependent mechanisms
Funded at Cardiff University · NIH-11015081 · Data updated 2026-11-12
This study is looking at how certain antibodies can help your immune system fight off viruses better, and it's for anyone interested in improving treatments for viral infections through better vaccines.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cardiff University NIH-funded |
| Lab location | 1 site (Cardiff, United Kingdom) |
| Project start | December 23, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $318,085 |
| NIH project number | 1R01AI186964-01 |
| Project ID | NIH-11015081 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would be individuals at risk of or currently infected with the 2019 novel coronavirus.
✕Less likely to help
Patients who are not infected with the virus or who have already developed strong immunity may not benefit from this research.
What this research studies
This research investigates how antibodies can activate the immune system to fight off virus infections, particularly focusing on mechanisms like antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP). The researchers aim to identify which antigens and epitopes are most effective in enhancing these immune responses. By analyzing infected cells and using advanced laboratory techniques, they hope to develop better vaccination strategies that not only neutralize viruses but also boost cellular immunity. This could lead to more effective treatments for viral infections.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and therapies that enhance the body's ability to fight viral infections.
How similar studies have gone: Other research has shown promise in enhancing immune responses through similar mechanisms, indicating potential for success in this approach.
Where this research is happening
-
Cardiff University
Cardiff, United Kingdom Active
Researchers
- Principal investigator: Stanton, Richard — Cardiff University
- Study coordinator: Stanton, Richard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.