Understanding how antibiotics affect patients with viral sepsis
Antibiotic Utilization Patterns and Impact on Outcomes for Patients with Respiratory Viral Sepsis
This study looks at how often antibiotics are given to people with respiratory viral sepsis, a condition that can be mistaken for bacterial infections, to help figure out when they really need them and to make sure patients get the safest and best care possible.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10907703 on NIH RePORTER |
What this research studies
This research investigates the patterns of antibiotic use in patients diagnosed with respiratory viral sepsis, a condition often confused with bacterial infections. It aims to clarify how frequently viruses cause sepsis and the potential harms associated with unnecessary antibiotic treatment. By analyzing extensive clinical data from over 200 hospitals, the study will identify which patients may not benefit from antibiotics and promote safer treatment practices. The ultimate goal is to improve patient safety and outcomes by refining current treatment guidelines.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with respiratory viral sepsis who may be receiving antibiotics.
Not a fit: Patients with bacterial sepsis or those not diagnosed with sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer treatment protocols for patients with viral sepsis, reducing unnecessary antibiotic use and associated harms.
How similar studies have performed: While the approach of analyzing antibiotic use in viral sepsis is gaining attention, this specific research aims to provide new insights and has not been extensively tested in prior studies.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Shappell, Claire — Brigham and Women's Hospital
- Study coordinator: Shappell, Claire
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.