Understanding how antibiotic-resistant Klebsiella pneumoniae spreads and causes infections
Regional genomic epidemiology to identify drivers of resistance, transmission and infection with carbapenem-resistant Klebsiella pneumoniae
This study is looking into how a tough-to-treat bacteria called carbapenem-resistant Klebsiella pneumoniae spreads in hospitals, so we can find better ways to protect patients from these serious infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10676174 on NIH RePORTER |
What this research studies
This research investigates the spread and resistance mechanisms of carbapenem-resistant Klebsiella pneumoniae (CRKP), a dangerous antibiotic-resistant bacteria. By analyzing genetic data and epidemiological factors, the study aims to identify how CRKP emerges and spreads within healthcare settings. Patients may benefit from improved understanding and potential strategies to combat these infections, which are known to have high mortality rates. The research will involve collaboration with healthcare networks to gather data on CRKP cases.
Who could benefit from this research
Good fit: Ideal candidates for this research include hospitalized patients who are at risk of or currently infected with carbapenem-resistant Klebsiella pneumoniae.
Not a fit: Patients who are not hospitalized or do not have infections related to antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for infections caused by antibiotic-resistant bacteria.
How similar studies have performed: Previous research has shown success in understanding antibiotic resistance through genomic epidemiology, indicating that this approach has potential for impactful findings.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Snitkin, Evan — University of Michigan at Ann Arbor
- Study coordinator: Snitkin, Evan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.