Understanding how antibiotic resistance spreads in a common throat and skin infection.
Official title: Macrolide resistance transfer in Streptococcus pyogenes
Funded at New York Medical College · NIH-10474268 · Data updated 2026-11-12
This study is looking into how certain germs that cause throat and skin infections can share their ability to resist antibiotics, which could help us find better ways to treat infections for people dealing with these tough bacteria.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York Medical College NIH-funded |
| Lab location | 1 site (Valhalla, United States) |
| Project start | August 24, 2021 |
| Project end | July 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $203,099 |
| NIH project number | 5R21AI156226-02 |
| Project ID | NIH-10474268 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from Group A Streptococcus infections, particularly those with antibiotic-resistant strains.
✕Less likely to help
Patients with infections caused by bacteria other than Group A Streptococcus may not benefit from this research.
What this research studies
This research investigates the mechanisms behind the transfer of antibiotic resistance in Group A Streptococcus (GAS), a bacterium responsible for many throat and skin infections. The study aims to identify the genetic elements that carry resistance genes and how these genes can be shared between different strains of GAS. By using experimental models, researchers will explore the conditions that facilitate this transfer, which is crucial for developing strategies to combat antibiotic resistance. The findings could lead to better treatment options for patients affected by resistant strains of GAS.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for infections caused by antibiotic-resistant bacteria, potentially saving lives.
How similar studies have gone: Previous research has shown success in understanding antibiotic resistance mechanisms in other bacterial pathogens, indicating that this approach could yield valuable insights.
Where this research is happening
-
New York Medical College
Valhalla, United States Active
Researchers
- Principal investigator: Bessen, Debra E — New York Medical College
- Study coordinator: Bessen, Debra E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.