Understanding how Annexin A6 affects the progression of aggressive breast cancer
Mechanisms of Annexin A6 Mediated Basal-like Breast Cancer Progression
This study is looking at how a protein called Annexin A6 affects triple negative breast cancer, which is a tough type of breast cancer, to help find better ways to treat it and predict how patients might respond to different therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Meharry Medical College NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10887533 on NIH RePORTER |
What this research studies
This research investigates the role of Annexin A6 in triple negative breast cancer (TNBC), a type of breast cancer known for its aggressive nature and poor response to treatment. The study focuses on how varying levels of Annexin A6 influence tumor growth, metastasis, and resistance to therapies like tyrosine kinase inhibitors. By examining the cellular mechanisms involved, the research aims to identify potential biomarkers for predicting treatment response and cancer relapse. Patients may benefit from insights that could lead to more effective treatment strategies tailored to their specific cancer profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with triple negative breast cancer who are seeking new treatment options.
Not a fit: Patients with non-triple negative breast cancer or those who are not currently undergoing treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better outcomes for patients with triple negative breast cancer.
How similar studies have performed: Previous research has shown promising results in understanding the role of biomarkers in cancer treatment, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, United States
- Meharry Medical College — Nashville, United States (Active)
Researchers
- Principal investigator: Sakwe, Amos Malle — Meharry Medical College
- Study coordinator: Sakwe, Amos Malle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.