NIH-funded research R21 grant

Understanding how animals detect and respond to chemical signals of danger

Official title: Exploring the mechanism of chemosensory detection of threatening kairomones and associated behavioral responses

Funded at University of Rochester · NIH-11045663 · Data updated 2026-11-12

This study is exploring how animals, like mice, use their sense of smell to detect danger from predators, specifically looking at how they react to certain chemicals found in snake poop.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startMarch 1, 2024
Project endFebruary 28, 2027
Funding year2025
Award (this year)$192,500
NIH project number5R21DC021736-02
Project IDNIH-11045663 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals interested in animal behavior, ecology, or those involved in wildlife conservation.

Less likely to help

Patients who are not interested in animal behavior or do not have a background in ecology may not find direct benefits from this research.

What this research studies

This research investigates how animals use their sense of smell to detect chemical signals that indicate threats, such as the presence of predators. By focusing on the accessory olfactory system, the study aims to uncover the specific molecules involved in these chemosensory processes and how they influence behavior. The researchers will utilize advanced machine learning techniques to analyze the behavioral responses of mice exposed to different chemical cues from snake feces. This approach will help clarify the relationship between chemical signals and behavioral changes in animals.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of animal behavior and improve strategies for managing wildlife interactions and conservation efforts.

How similar studies have gone: Previous research has shown success in understanding chemosensory detection in animals, but this specific approach using machine learning is relatively novel.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Wang, Jinxin — University of Rochester
  • Study coordinator: Wang, Jinxin

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.