Understanding how anesthesia affects brain networks
Elucidating dynamic reorganization of whole-brain networks during anesthetic-induced unconsciousness
This study is looking at how different types of anesthesia make you unconscious by exploring how they change the way different parts of the brain communicate with each other, using animal models to find common patterns that help us understand how anesthesia works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project ID | NIH-10861730 on NIH RePORTER |
What this research studies
This research investigates how different anesthetic agents cause unconsciousness by examining the dynamic changes in brain networks. Using advanced imaging techniques, the study will analyze how information exchange across large brain regions is disrupted during anesthesia. By observing animal models, researchers aim to identify common patterns of brain activity and connectivity that occur with various anesthetics. This approach allows for a deeper understanding of the neural mechanisms behind anesthetic-induced unconsciousness.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include patients undergoing surgeries that require anesthesia.
Not a fit: Patients who are not undergoing surgical procedures or those who do not require anesthesia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved anesthetic techniques and better patient outcomes during surgical procedures.
How similar studies have performed: Other research has shown success in using imaging techniques to study brain activity during anesthesia, indicating that this approach has potential for meaningful insights.
Where this research is happening
University Park, United States
- Pennsylvania State University, the — University Park, United States (Active)
Researchers
- Principal investigator: Zhang, Nanyin — Pennsylvania State University, the
- Study coordinator: Zhang, Nanyin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.