Understanding how ancestry affects wound healing
Biomaterial Models of Ancestral Contributions to Wound Healing
This project aims to understand how a person's ancestry influences how their body heals after an injury, hoping to create more personalized treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project ID | NIH-11126738 on NIH RePORTER |
What this research studies
This project explores how a person's ancestry influences how their body heals from injuries. We are focusing on specific skin cells (dermal fibroblasts) and immune cells (monocytes and macrophages) that play key roles in tissue repair. Using a special gel model, we observe how these cells from different ancestries communicate and respond to stress, mimicking a wound. This helps us understand why some people heal differently and could lead to more tailored treatments.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation but aims to benefit individuals who experience complications with tissue regeneration and wound healing.
Not a fit: Patients whose wound healing issues are not related to ancestral differences in cellular responses may not directly benefit from this specific line of research.
Why it matters
Potential benefit: If successful, this work could lead to new, personalized treatments that improve how individuals heal from wounds based on their unique ancestral background.
How similar studies have performed: While the role of ancestry in health is increasingly recognized, this specific approach using biomaterial models to link ancestry to cellular wound healing mechanisms is a novel area of investigation.
Where this research is happening
College Park, United States
- Univ of Maryland, College Park — College Park, United States (Active)
Researchers
- Principal investigator: Moore, Erika Michelle — Univ of Maryland, College Park
- Study coordinator: Moore, Erika Michelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.