Understanding how Alzheimer's disease progresses using genetic and imaging data
Characterizing the progression of Alzheimer's disease with multi-omic genetic and imaging data
['FUNDING_R01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10802970
This study is looking at how Alzheimer's disease changes over time by examining genes and brain scans, with the goal of finding clues that can help doctors spot the disease earlier and tailor treatments for people at different stages.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INDIANA UNIVERSITY INDIANAPOLIS (nih funded) |
| Locations | 1 site (INDIANAPOLIS, UNITED STATES) |
| Trial ID | NIH-10802970 on ClinicalTrials.gov |
What this research studies
This research investigates the progression of Alzheimer's disease (AD) by analyzing genetic and brain imaging data. It aims to identify specific genetic biomarkers that can indicate different stages of AD and help differentiate between various clinical trajectories. By utilizing advanced computational methods and existing multi-omic datasets, the study seeks to enhance early diagnosis and improve patient stratification for clinical trials. This could lead to more targeted therapeutic interventions for individuals at risk of developing AD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease or those in the early stages of the condition.
Not a fit: Patients with advanced Alzheimer's disease or those without any genetic predisposition to the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more personalized treatment options for patients with Alzheimer's disease.
How similar studies have performed: Previous research has shown promise in using multi-omic approaches to understand Alzheimer's disease, suggesting that this methodology could yield valuable insights.
Where this research is happening
INDIANAPOLIS, UNITED STATES
- INDIANA UNIVERSITY INDIANAPOLIS — INDIANAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YAN, JINGWEN — INDIANA UNIVERSITY INDIANAPOLIS
- Study coordinator: YAN, JINGWEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease biological marker, Alzheimer's disease patient