Understanding how alcohol and metabolic risks affect liver disease progression
Estimating the Contribution of Alcohol and Metabolic Risk to Liver Disease Progression to Inform Personalized Interventions
This study is looking at how drinking alcohol and other health factors affect liver diseases like alcoholic liver disease and non-alcoholic fatty liver disease, and it aims to find ways to help people based on their unique health profiles.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10897225 on NIH RePORTER |
What this research studies
This research investigates the combined effects of alcohol consumption and metabolic risk factors on the progression of liver diseases, specifically alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). By analyzing data from a large cohort over 35 years, the study aims to identify how different profiles, such as age, sex, and race, influence liver health. The researchers will also explore novel biomarkers to develop personalized interventions for preventing and treating liver disease. This approach seeks to create tailored strategies for monitoring and managing liver health based on individual risk factors.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals over 21 years old who consume alcohol and have metabolic risk factors related to liver disease.
Not a fit: Patients with liver disease not related to alcohol or metabolic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment plans that significantly improve liver health outcomes for patients at risk.
How similar studies have performed: Previous research has shown promising results in understanding the interactions between alcohol use and metabolic risks in liver disease, indicating that this approach has potential for success.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Lee, Brian Pei Lim — University of Southern California
- Study coordinator: Lee, Brian Pei Lim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.