Understanding how alcohol affects pain relief in mice
Official title: Elucidating causal mechanisms of ethanol-induced analgesia in BXD recombinant inbred mouse lines
Funded at Virginia Commonwealth University · NIH-10938304 · Data updated 2026-11-12
This study is looking at how certain genes in mice affect the way alcohol can help relieve pain, which could give us insights into how alcohol might be used for pain management in people.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | September 10, 2023 |
| Project end | September 9, 2026 |
| Funding year | 2024 |
| Award (this year) | $43,404 |
| NIH project number | 5F31AA030918-02 |
| Project ID | NIH-10938304 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with chronic pain conditions who may be using alcohol as a coping mechanism.
✕Less likely to help
Patients who do not experience chronic pain or do not use alcohol for pain relief are unlikely to benefit from this research.
What this research studies
This research investigates the genetic factors that influence how alcohol can relieve pain in mice. By studying different mouse lines, the project aims to identify specific genes that contribute to the analgesic effects of ethanol. The approach combines genetic analysis, behavioral assessments, and transcriptomic studies to uncover the biological mechanisms behind alcohol-induced pain relief. This could help in understanding the relationship between alcohol use and pain management.
Why it matters
Potential benefit: If successful, this research could lead to better pain management strategies that minimize the risks associated with alcohol use.
How similar studies have gone: Previous studies have shown genetic influences on alcohol-induced analgesia, but this research aims to explore this area more comprehensively, making it a novel approach.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Rogers, Walker David — Virginia Commonwealth University
- Study coordinator: Rogers, Walker David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.