Understanding how alcohol affects pain relief in mice
Elucidating causal mechanisms of ethanol-induced analgesia in BXD recombinant inbred mouse lines
['FUNDING_FELLOWSHIP'] · VIRGINIA COMMONWEALTH UNIVERSITY · NIH-10938304
This study is looking at how certain genes in mice affect the way alcohol can help relieve pain, which could give us insights into how alcohol might be used for pain management in people.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA COMMONWEALTH UNIVERSITY (nih funded) |
| Locations | 1 site (RICHMOND, UNITED STATES) |
| Trial ID | NIH-10938304 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic factors that influence how alcohol can relieve pain in mice. By studying different mouse lines, the project aims to identify specific genes that contribute to the analgesic effects of ethanol. The approach combines genetic analysis, behavioral assessments, and transcriptomic studies to uncover the biological mechanisms behind alcohol-induced pain relief. This could help in understanding the relationship between alcohol use and pain management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic pain conditions who may be using alcohol as a coping mechanism.
Not a fit: Patients who do not experience chronic pain or do not use alcohol for pain relief are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better pain management strategies that minimize the risks associated with alcohol use.
How similar studies have performed: Previous studies have shown genetic influences on alcohol-induced analgesia, but this research aims to explore this area more comprehensively, making it a novel approach.
Where this research is happening
RICHMOND, UNITED STATES
- VIRGINIA COMMONWEALTH UNIVERSITY — RICHMOND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROGERS, WALKER DAVID — VIRGINIA COMMONWEALTH UNIVERSITY
- Study coordinator: ROGERS, WALKER DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.