Understanding how airway cells respond to viral infections
Official title: The innate antiviral response in airway epithelium: a cell type-resolved, functional genomics approach
Funded at Icahn School of Medicine at Mount Sinai · NIH-10996339 · Data updated 2026-11-12
This study is looking at how different cells in your airways help fight off viruses like COVID-19, and it hopes to find ways to boost your body's immune response to improve treatments for respiratory infections.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 1F31HL176050-01 |
| Project ID | NIH-10996339 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with respiratory conditions such as asthma or COPD, as well as those who have been affected by viral infections like COVID-19.
✕Less likely to help
Patients with non-respiratory conditions or those who do not have a history of viral infections may not receive direct benefits from this research.
What this research studies
This research investigates the role of different types of cells in the airway epithelium in responding to viral infections, particularly focusing on how these cells produce immune responses. By using advanced genomic techniques, the study aims to identify how various airway cells, such as secretory cells and basal cells, contribute to the body's defense against viruses like COVID-19. Patients may benefit from insights gained about how to enhance antiviral responses in the airway, potentially leading to better treatments for respiratory infections.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating viral infections in the respiratory system.
How similar studies have gone: Other research has shown promising results in understanding immune responses in airway cells, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Pankow, Alec P — Icahn School of Medicine at Mount Sinai
- Study coordinator: Pankow, Alec P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.