Understanding how airway cells interact with immune cells in lung diseases
Official title: Mapping Airway Epithelial Cell-Immune Cell Interactions in Lung Health and Disease
Funded at Massachusetts General Hospital · NIH-10974664 · Data updated 2026-11-12
This study is looking at how the cells in your airways and your immune system work together in asthma and COPD, hoping to find new ways to understand and treat these conditions.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $798,062 |
| NIH project number | 1U01HL175384-01 |
| Project ID | NIH-10974664 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with asthma or COPD, particularly those experiencing severe symptoms or complications.
✕Less likely to help
Patients with other respiratory conditions unrelated to asthma or COPD may not benefit from this research.
What this research studies
This research investigates the interactions between airway epithelial cells and immune cells in conditions like asthma and chronic obstructive pulmonary disease (COPD). By examining how these cells communicate and respond to various stimuli, the study aims to uncover the underlying mechanisms that contribute to these inflammatory diseases. The research will focus on identifying specific cell types and their roles in the immune response, which could lead to new insights into disease progression and potential treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for asthma and COPD, enhancing patient outcomes and quality of life.
How similar studies have gone: Previous research has shown promise in understanding immune cell interactions in respiratory diseases, but this study aims to explore novel aspects that have not been extensively investigated.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Medoff, Benjamin David — Massachusetts General Hospital
- Study coordinator: Medoff, Benjamin David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.