Understanding how air pollution affects heart and lung health
Identifying Multidimensional Omics Profiles Associated with Cardiovascular and Pulmonary Responses to Chronic and Acute Air Pollution Exposure (Project 2) for AIRHEALTH Study
This study is looking at how air pollution affects lung and heart health by checking how it causes inflammation in the body, and it's for people who want to understand how pollution might impact their health and what new treatments could help.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11086433 on NIH RePORTER |
What this research studies
This research investigates the effects of air pollution on lung and heart diseases by examining how it triggers inflammation in the body. Researchers will analyze blood samples from individuals exposed to air pollution to identify specific molecular responses, particularly focusing on a protein called IL-1β that may play a key role in these inflammatory processes. By using advanced systems biology approaches, the study aims to uncover the complex interactions between air pollution and immune responses, which could lead to new therapeutic strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with existing lung or heart conditions who have been exposed to air pollution.
Not a fit: Patients without any cardiovascular or pulmonary diseases or those not exposed to air pollution may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from cardiovascular and pulmonary diseases linked to air pollution.
How similar studies have performed: Previous research has shown promising results in understanding the inflammatory responses to air pollution, making this approach both relevant and potentially impactful.
Where this research is happening
Boston, United States
- Harvard School of Public Health — Boston, United States (Active)
Researchers
- Principal investigator: Kasowski, Maya — Harvard School of Public Health
- Study coordinator: Kasowski, Maya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.