Understanding how aging increases liver cancer risk
Core A: Administrative
This study is looking into why older adults are more likely to develop liver cancer and aims to find new ways to detect and prevent it early, so that patients can benefit from better screening and care.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanford Burnham Prebys Medical Discovery Institute NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10908387 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms that contribute to the higher incidence of hepatocellular carcinoma (HCC) in older adults. By assembling a team of experts in cancer and aging biology, the project aims to develop innovative methods for early detection and prevention of liver cancer. The research utilizes advanced mouse models and bioinformatics tools to explore the cellular changes associated with aging and cancer. Patients may benefit from improved screening and preventive strategies derived from this work.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are older adults at risk for liver cancer, particularly those with underlying liver conditions.
Not a fit: Patients who are younger and have no risk factors for liver cancer may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better prevention strategies for liver cancer in older adults.
How similar studies have performed: Other research has shown promise in understanding cancer mechanisms related to aging, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- Sanford Burnham Prebys Medical Discovery Institute — La Jolla, United States (Active)
Researchers
- Principal investigator: Adams, Peter D. — Sanford Burnham Prebys Medical Discovery Institute
- Study coordinator: Adams, Peter D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.