Understanding how aging cells affect health and disease
Cellular Senescence Network (SenNet) Consortium Organization and Data Coordinating Center (CODCC)
The Cellular Senescence Network Consortium is studying how aging cells work and how they might contribute to diseases like cancer and brain disorders, with the hope that their findings will help develop better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10926860 on NIH RePORTER |
What this research studies
The Cellular Senescence Network Consortium (SenNet) aims to explore the biology of aging cells and their role in various diseases. By coordinating data from multiple research teams, SenNet will investigate how these cells behave under different conditions, including normal aging and disease states. This research involves advanced techniques in single-cell genomics to map and analyze cellular changes, which could lead to new insights into health issues like cancer and neurological disorders. Patients may benefit from the findings as they could inform future treatments and interventions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals experiencing age-related health issues or those with conditions influenced by cellular senescence.
Not a fit: Patients with acute, non-age-related conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating age-related diseases and conditions.
How similar studies have performed: Previous research in cellular senescence has shown promising results, indicating that understanding these cells can lead to significant advancements in treating age-related diseases.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Silverstein, Jonathan C. — University of Pittsburgh at Pittsburgh
- Study coordinator: Silverstein, Jonathan C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.