Understanding how aging and COVID-19 affect brain health
Official title: GXI Interactions
Funded at University of Texas Hlth Science Center · NIH-10907435 · Data updated 2026-11-12
This study is looking at how COVID-19 affects brain health in older adults and what biological factors might help some people age healthily, so we can better understand how to support brain function during and after the virus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $604,090 |
| NIH project number | 5U19AG076581-02 |
| Project ID | NIH-10907435 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include older adults aged 65 and above, particularly those who have experienced COVID-19 or are at risk of neurological complications.
✕Less likely to help
Patients under the age of 65 or those without a history of COVID-19 may not receive direct benefits from this research.
What this research studies
This research investigates the biological factors that contribute to healthy brain aging, particularly in the context of COVID-19. It aims to understand how the SARS-CoV-2 virus impacts neurological functions and cognitive health in older adults. By examining both genetic and environmental influences, the study seeks to identify variations in how individuals respond to the virus and its effects on brain health. The research will involve analyzing data from diverse populations to uncover insights into the neurobiological responses to COVID-19.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining cognitive health in older adults affected by COVID-19.
How similar studies have gone: While research on COVID-19's impact on neurological health is emerging, this specific approach to understanding genetic and environmental factors in brain aging is relatively novel.
Where this research is happening
-
University of Texas Hlth Science Center
San Antonio, United States Active
Researchers
- Principal investigator: Blangero, John — University of Texas Hlth Science Center
- Study coordinator: Blangero, John
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.