Understanding how aging affects women's health and chronic diseases
The Microvascular Aging and Eicosanoids - Women's Evaluation of Systemic Aging Tenacity (MAE-WEST) ("You are never too old to become younger!") Specialized Center for Research Excellence (SCORE)
['FUNDING_OTHER'] · CEDARS-SINAI MEDICAL CENTER · NIH-11083397
This study is looking at how women age differently than men, especially when it comes to chronic diseases like Alzheimer's and heart failure, and it aims to understand the biological reasons behind these differences to improve treatment options for women.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CEDARS-SINAI MEDICAL CENTER (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11083397 on ClinicalTrials.gov |
What this research studies
This research investigates how women age differently than men, particularly focusing on the prevalence of chronic diseases like Alzheimer's and heart failure. It explores the role of microvascular aging and systemic inflammation in these differences, particularly through the study of eicosanoids, which are bioactive lipids involved in inflammation. By examining how these factors contribute to multi-organ dysfunction in women, the research aims to uncover the underlying mechanisms that lead to age-related health disparities. Patients may be involved in assessments that help identify these biological differences and their implications for treatment.
Who could benefit from this research
Good fit: Ideal candidates for participation are women experiencing age-related health issues, particularly those related to Alzheimer's disease and other chronic conditions.
Not a fit: Patients who are not women or those who do not have age-related chronic diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of age-related diseases in women.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and chronic diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
LOS ANGELES, UNITED STATES
- CEDARS-SINAI MEDICAL CENTER — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHENG, SUSAN — CEDARS-SINAI MEDICAL CENTER
- Study coordinator: CHENG, SUSAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease or a related dementia, Alzheimer's disease or a related disorder, Alzheimer's disease or related dementia