Understanding how aging affects women differently than men in relation to Alzheimer's disease and other conditions
MAE-WEST SCORE Project 2 Clinical
This study looks at how aging affects women and men differently, especially in relation to Alzheimer's disease, and it aims to understand how stress and inflammation might play a role in this, so we can find better ways to help women who are at higher risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903840 on NIH RePORTER |
What this research studies
This research investigates the differences in aging between women and men, particularly focusing on how these differences contribute to the development of Alzheimer's disease and related dementias. It explores the role of chronic stressors and inflammatory mediators in multi-organ aging and dysfunction. By examining these factors, the research aims to identify common pathways that lead to increased disease prevalence in women, which could inform targeted interventions. Patients may be involved in studies assessing these mechanisms and their implications for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing age-related cognitive decline or those at risk for Alzheimer's disease and related dementias.
Not a fit: Patients who are not female or those who do not have concerns related to aging or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for Alzheimer's disease and related conditions in women.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and disease prevalence, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bairey Merz, Cathleen Noel — Cedars-Sinai Medical Center
- Study coordinator: Bairey Merz, Cathleen Noel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.