Understanding how aging affects women differently than men in relation to Alzheimer's disease and other conditions.
MAE-WEST SCORE Leadership Administrative Core
This study is looking at how aging affects men and women differently, especially in relation to Alzheimer's disease, to find out why women are more likely to develop it and to discover better ways to help prevent and treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903834 on NIH RePORTER |
What this research studies
This research investigates the differences in aging between men and women, particularly focusing on how these differences contribute to the development of Alzheimer's disease and related dementias. It aims to explore the biological mechanisms behind the female predominance in these conditions, looking at factors such as inflammation and microvascular dysfunction. By understanding these sex-specific pathways, the research seeks to identify effective interventions that could reduce the burden of age-related diseases in women. Patients may benefit from insights that could lead to tailored treatments and preventive strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include women who are experiencing age-related cognitive decline or have a family history of Alzheimer's disease.
Not a fit: Patients who are younger than 50 or those without any risk factors for Alzheimer's disease may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for Alzheimer's disease and related dementias specifically for women.
How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bairey Merz, Cathleen Noel — Cedars-Sinai Medical Center
- Study coordinator: Bairey Merz, Cathleen Noel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.