Understanding how aging affects women differently than men in Alzheimer's disease

MAE-WEST SCORE Research Support Core - Bioinformatics Core

NIH-funded research Cedars-Sinai Medical Center · NIH-10903836

This study is looking at how men and women age differently and how those differences might affect the risk of developing Alzheimer's disease, especially in women, by examining the impact of stress and inflammation on overall health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10903836 on NIH RePORTER

What this research studies

This research investigates the differences in biological aging between men and women, particularly focusing on how these differences contribute to the development of Alzheimer's disease and related dementias. It explores the role of chronic stressors and inflammatory mediators in multi-organ aging and dysfunction. By analyzing biological markers and utilizing bioinformatics, the study aims to uncover the mechanisms behind the higher prevalence of Alzheimer's disease in women as they age. This could lead to targeted interventions that address the unique health challenges faced by women.

Who could benefit from this research

Good fit: Ideal candidates for this research are older women who are at risk for or experiencing symptoms of Alzheimer's disease and related dementias.

Not a fit: Patients who are younger or do not have a risk of Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for Alzheimer's disease specifically tailored for women.

How similar studies have performed: Previous research has shown promising results in understanding sex differences in aging and disease, indicating that this approach has potential for success.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementia
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.