NIH-funded research R01 grant

Understanding how aging affects treatment outcomes in older adults with colorectal cancer

Official title: Geriatric assessment domains in relation to treatment outcomes among older adults with colorectal cancer

Funded at University of Utah · NIH-11132889 · Data updated 2026-11-12

This study is looking at how getting older affects the success of treatments for older adults with colorectal cancer, so we can better personalize care and improve their quality of life.

More Colorectal Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Utah
NIH-funded
Lab location1 site (Salt Lake City, United States)
Project startJuly 15, 2024
Project endMarch 31, 2029
Funding year2025
Award (this year)$759,334
NIH project number5R01AG083580-02
Project IDNIH-11132889 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 70 and above who have been diagnosed with colorectal cancer.

Less likely to help

Patients who are younger than 70 or those without a diagnosis of colorectal cancer may not benefit from this research.

What this research studies

This research investigates the impact of aging on treatment outcomes for older adults diagnosed with colorectal cancer. It aims to evaluate various factors such as physical function, a brief geriatric assessment tool, and specific biomarkers related to aging. By analyzing these elements, the study seeks to improve clinical decision-making and tailor treatment plans that minimize complications and enhance the quality of life for older patients. The research will focus on understanding how these aging-related factors influence surgical outcomes and overall patient well-being.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for older adults with colorectal cancer, ultimately improving their survival rates and quality of life.

How similar studies have gone: Previous research has shown that tailored approaches considering aging factors can improve outcomes in older cancer patients, suggesting this study builds on established concepts.

Where this research is happening

  • University of Utah
    Salt Lake City, United States
    Active

Researchers

  • Principal investigator: Hardikar, Sheetal — University of Utah
  • Study coordinator: Hardikar, Sheetal

Related research

Other NIH-funded projects on the same topics.

  • How aging, physical function, and health markers relate to recovery after colorectal cancer

    It looks at whether physical function, a short geriatric checklist, and pre-surgery blood markers of aging predict surgery complications and quality of life for older adults with colorectal cancer.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11306683

  • Geriatric assessments to guide cancer care for older adults with advanced cancer

    A study tests a geriatric assessment–based approach to tailor cancer treatment in older adults with advanced cancer to reduce side effects and keep patients at home longer.

    NIH research University of Rochester · Rochester, United States · NIH-11452992

  • Improving care for older adults living with HIV

    This study is working to improve care for older adults living with HIV by creating a helpful guide that addresses their unique health and social needs, and it involves input from both patients and experts to make sure it's useful for doctors who may not specialize in elderly care.

    NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-10973225

  • Improving colorectal cancer screening and follow-up care.

    This study is working to help more people get screened for colorectal cancer and receive the follow-up care they need, especially those who haven't been screened much before, so that everyone can have better access to important health checks and improve their overall health.

    NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-9627071

  • Colorectal cancer prognosis through a broad, collaborative study

    A large, multi-center study follows people newly diagnosed with colorectal cancer to find biomarkers and patterns that predict outcomes and guide future care.

    NIH research Utah State Higher Education System--University of Utah · Salt Lake City, United States · NIH-11590756

  • HOME: Smart, compassionate AI helpers for aging at home

    A research project is developing an AI-powered, multimodal system to help older adults stay safe and healthy at home while supporting busy caregivers.

    NIH research University of California, Merced · Merced, United States · NIH-11579078

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.