Understanding how aging affects tongue muscle fatigue and swallowing
Bioenergetic Mechanisms of Tongue Muscle Fatigue
This study is looking at how tongue muscle fatigue affects swallowing in older adults and will test if tongue exercises and special stimulation can help improve muscle function, which could lead to better treatments for swallowing difficulties as we age.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10647662 on NIH RePORTER |
What this research studies
This research investigates the bioenergetic mechanisms behind tongue muscle fatigue, particularly in older adults. It aims to understand how changes in muscle metabolism contribute to swallowing difficulties as people age. By using a rat model, the study will explore the effects of tongue exercises and neuromuscular stimulation on muscle function and fatigue. The findings could lead to improved treatments for age-related swallowing impairments.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing swallowing difficulties due to muscle fatigue.
Not a fit: Patients who are younger or do not have swallowing impairments related to muscle fatigue may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective interventions for swallowing difficulties in older adults.
How similar studies have performed: While the specific focus on tongue muscle fatigue in aging is novel, similar studies have shown success in understanding muscle fatigue and interventions in other muscle groups.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Connor, Nadine P — University of Wisconsin-Madison
- Study coordinator: Connor, Nadine P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.