Understanding how aging affects the retina
Identifying Molecular Mechanisms Regulating Retinal Aging
['FUNDING_FELLOWSHIP'] · JOHNS HOPKINS UNIVERSITY · NIH-11059039
This study is looking at how aging affects the cells in our eyes and how that might lead to vision problems, with the hope of finding new ways to help keep our eyesight healthy as we get older.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11059039 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular mechanisms that regulate aging in the retina, particularly focusing on how cellular aging contributes to degenerative eye diseases. By utilizing advanced techniques that allow for single-cell analysis, the study aims to uncover specific changes in gene regulation that occur as the retina ages. The research will also explore how acute injuries to the retina may accelerate aging processes, with the goal of identifying potential therapeutic targets to slow or prevent age-related vision loss.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are at risk of or experiencing age-related retinal degeneration.
Not a fit: Patients under the age of 65 or those with retinal conditions unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow down or prevent age-related blindness.
How similar studies have performed: Previous research has shown promise in understanding cellular aging mechanisms, but this specific approach focusing on retinal aging is relatively novel.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PALAZZO, ISABELLA — JOHNS HOPKINS UNIVERSITY
- Study coordinator: PALAZZO, ISABELLA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.