Understanding how aging affects the brain's ability to connect events over time
Official title: Uncovering Neural Substrates of Diminished Temporal Binding Capacity in Aging
Funded at New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10708806 · Data updated 2026-11-12
This study looks at how aging and certain brain disorders affect the way our brains connect different experiences and memories, especially focusing on a part of the brain called the hippocampus, to help find new ways to support better thinking and emotional health in older adults.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 30, 2022 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $199,875 |
| NIH project number | 5R21AG079025-02 |
| Project ID | NIH-10708806 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing cognitive decline or related neuropsychiatric symptoms.
✕Less likely to help
Patients who are not experiencing cognitive decline or are younger adults may not benefit from this research.
What this research studies
This research investigates how the brain's ability to link different stimuli and events diminishes with aging and related neuropsychiatric disorders. It focuses on understanding the neural changes that contribute to this decline, which is crucial for cognitive and emotional health in older adults. By studying specific brain regions, particularly the hippocampus, the research aims to uncover the underlying mechanisms that lead to these impairments. The findings could pave the way for new interventions to improve cognitive function in aging populations.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing cognitive and emotional health in older adults.
How similar studies have gone: Previous research has shown promising results in understanding brain function related to cognitive processes, suggesting that this approach could yield valuable insights.
Where this research is happening
-
New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
New York, United States Active
Researchers
- Principal investigator: Turi, Gergely — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Turi, Gergely
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.