Understanding how aging affects the brain and Alzheimer's disease using advanced imaging techniques
Multiscale Modeling of Brain Aging and Alzheimer’s Disease with MRI, Pathology and Proteomics
This study is looking at how getting older affects the brain and can lead to Alzheimer's and similar conditions, using special imaging techniques to spot early signs of brain changes, which could help identify people at risk and lead to ways to prevent Alzheimer's.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10933720 on NIH RePORTER |
What this research studies
This research investigates how aging impacts the brain and contributes to Alzheimer's disease and related dementias. By utilizing advanced diffusion MRI techniques, the study aims to identify early signs of brain aging and neurodegeneration, which could help in recognizing individuals at risk. The approach focuses on understanding the role of white matter and various pathological processes involved in brain aging. Patients may benefit from insights that could lead to preventive measures against Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those over 100 years old, who may be at risk for Alzheimer's disease or related dementias.
Not a fit: Patients who are not experiencing cognitive decline or do not have risk factors for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and intervention strategies for Alzheimer's disease, improving patient outcomes.
How similar studies have performed: Previous research using advanced imaging techniques has shown promise in understanding brain aging and Alzheimer's disease, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Fieremans, Els — New York University School of Medicine
- Study coordinator: Fieremans, Els
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.