Understanding how aging affects the body and exploring ways to rejuvenate it
Molecular signature of parabiosis
This study is looking at how aging affects our bodies and can lead to diseases, with the goal of finding ways to help older adults feel healthier by exploring the changes in their cells and organs over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11076762 on NIH RePORTER |
What this research studies
This research investigates the biological processes of aging and how they contribute to various chronic diseases. By examining the molecular signatures associated with aging in different organs and cell types, the study aims to identify potential therapeutic targets for rejuvenation. The approach includes advanced techniques like RNA sequencing to analyze changes over time in aging mice, particularly focusing on the effects of shared circulation between young and old mice. This could lead to insights on how to improve health outcomes for older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who may be experiencing age-related health issues.
Not a fit: Patients under the age of 65 or those without age-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that prevent or mitigate age-related diseases, improving the quality of life for older adults.
How similar studies have performed: Previous research has shown promising results in rejuvenation approaches, but this study aims to explore novel methodologies that have not been extensively tested.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Wyss-Coray, Tony — Stanford University
- Study coordinator: Wyss-Coray, Tony
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.